Lyme disease, also called Lyme Borreliosis, typically affects people who spend time in wooded areas of the upper Midwest and the Northeast United States, where the disease spreads via deer ticks and western black-legged ticks.

Suspected cases of Lyme disease can be treated before symptoms appear. More advanced cases of Lyme disease may share some symptoms with fibromyalgia, such as fatigue, stiffness, arthritis pain, extreme headaches, sleep problems, and difficulty concentrating. Symptoms may come and go, sometimes returning years later.